CDDO induces apoptosis via the intrinsic pathway in lymphoid cells
نویسندگان
چکیده
منابع مشابه
The triterpenoid CDDO induces apoptosis in refractory CLL B cells.
Chronic lymphocytic leukemia (CLL) cells develop chemo-resistance over time. Most anticancer agents function through induction of apoptosis, and therefore resistance against these agents is likely to be caused by selection for CLL cells with defects in the particular apoptosis pathway that is triggered by these drugs. Anticancer agents that function through alternative apoptotic pathways might ...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2004
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2403328